45. How does the
depolarization of the neuronal
membrane start?

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The primary cause of neuronal
depolarization is the of
neurotransmitters released in
synapse (by the axon the neuron that
sent signal) to specific receptors
the membrane of the that is
receiving the . The binding of
neurotransmitters those receptors is
a phenomenon that alters the
permeability of the region
the binding causes sodium
to open. When positive
ions enter the cell favour of their
concentration , the membrane
voltage increases, lessening the
negative polarization. this
depolarization reaches the
threshold (about –50 mV)
depolarization continues, the action
reached and the impulse
transmitted along the cell .